设为首页 | 加入收藏
| 欢迎光临本站!

我的博文

无效食管运动与胃食管反流病关系的探讨

(2014-10-22 12:22:17)

    【摘要】
        目的 探讨无效食管运动(IEM)与胃食管反流病(GERD)的关系。
        方法 对90例GERD全部进行胃镜检查并做食管压力测定和24 h食管动态pH监测,其中反流性食管炎(RE)组62例,非糜烂性反流病(NERD)组28例。研究IEM与食管酸暴露及RE的关系。
        结果 RE组中确诊IEM 30例(48.4%)明显高于NERD组6例(21.4%)(P<0.05)。36例IEM患者33例(91.7%)食管酸暴露阳性,高于食管动力正常患者(28/49,57.2%)(P<0.01);远端食管pH<4总反流时间、卧位反流时间百分比、>5 min长反流周期数、最长反流时间、DeMeester评分IEM者明显高于食管动力正常者(P<0.01),反流周期数前者明显高于后者(P<0.05)。
        结论 IEM在GERD中较常见,其食管动力障碍中绝大多数为IEM,IEM与食管远端酸暴露及RE密切相关。
    【关键词】胃食管反流;食管pH监测;无效食管运动;酸暴露;压力测定


    【Abstract】
    Objective   To investigate the correlation between ineffective esophageal motility (IEM) and gastroesophageal reflux disease (GERD).
    Methods   A total of 90 GERD patients were enrolled in our study, including 62 patients with reflux esophagitis (RE) and 28 with non-erosive reflux disease (NERD). All the patients underwent gastroscopy, 24-hour esophageal pH monitoring and esophageal manometry.
    Results   In the RE group 30 (48.4%) patients were diagnosed as having IEM, which was significantly higher than the NERD group (6 patients, 21.4%) (P<0.05). Positive esophageal acid exposure was more often seen in patients with IEM than in those with normal esophageal motility (91.7% v.s. 57.2%, P<0.01). The values of total percentage of time with pH<4, percentage of reflux time in supine position, long-duration episodes (>5 min) and the longest reflux time and DeMeester score were significantly higher in the IEM cases than those in the normal esophageal motility cases (P<0.01), so was the values of number of reflux episodes (P<0.05).
    Conclusion   IEM is the most common esophageal dysmotility in patients with GERD and closely related to distal esophageal acid exposure and RE.
    【Key words】Gastroesophageal reflux;Esophageal pH monitoring;Ineffective esophageal motility;Acid exposure; Manometry

阅读(1954)评论(0)转载(0)收藏(0)
发布评论
用户名: 登录
全部评论
个人资料
    任旭 单位:黑龙江省医院南岗分院
    所属科室:消化科
    出生:1974-03-10
更多>>相册
更多>>推荐博文