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硫酸镁溶液联合复方聚乙二醇电解质散在胶囊内镜检查前肠道准备中的价值

(2014-10-22 12:26:59)

    【摘要】
        目的 探讨硫酸镁联合复方聚乙二醇电解质散在胶囊内镜检查术前肠道准备中的应用价值。

    方法 81例患者分成单纯口服复方聚乙二醇电解质散组(A组,n=41)和硫酸镁联合复方聚乙二醇电解质散口服组(B组,n=40),比较两组病变检出情况、肠道准备评分结果、胶囊滞留发生情况及电解质、肝肾功能检测结果。

    结果 A组病变检出率为65.9%(27/41),B组为62.5%(25/40),差异无统计学意义(χ2=0.099,P>0.05);A组肠道准备评分≤4分19例、≥6分22例,B组≤4分28例、≥6分12例,差异有统计学意义(χ2=4.653,P<0.05);A组胶囊滞留发生率为2.4%(1/41),B组为5.0%(2/40),差异无统计学意义(χ2=0.372,P>0.05)。两组患者服用肠道准备药物过程中均无明显腹痛、恶心、呕吐、心慌等不适,服药后两组电解质水平及肝肾功能指标值比较差异均无统计学意义(P>0.05)。

    结论 硫酸镁联合复方聚乙二醇电解质散应用于胶囊内镜检查术前肠道准备具有较好的应用价值。
      【关键词】胶囊内窥镜检查;硫酸镁;复方聚乙二醇电解质散;肠道准备

    Magnesium sulfate combined with compound polyethylene glycol electrolyte in the bowel preparation before capsule endoscopy
    CHEN Xu, LI Peng, WANG Yong-jun, ZONG Ye, WU Yong-dong, YU Zhong-lin, ZHANG Shu-tian.Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University,Beijing 100050,China
    Corresponding author: LI Peng

    【Abstract】
    Objective  To evaluate magnesium sulfate and compound polyethylene glycol electrolyte in bowel preparation before capsule endoscopy.

    Methods  A total of 81 patients were randomly divided into two groups. Group A (n=41) received compound polyethylene glycol electrolyte, and group B (n=40) received magnesium sulfate combined with compound polyethylene glycol electrolyte. Positive detection rate, intestinal preparation score, the incidence of capsule retention and solution quality, liver and kidney function were compared between those two groups.

    Results  The positive detection rates of capsule endoscopy were 65.9% (27/41) in group A and 62.5% (25/40) in group B, which were nonsignificantly different (χ2=0.099,P>0.05). The intestinal preparation scores of 19 patients in group A were ≤4 and those of 22 patients were ≥6, while those of 28 patients in group B were ≤4 and of 12 patients were ≥6, which were significantly different (χ2=4.653,P<0.05). The rates of capsule retention of group A and B were 2.4% (1/41) and 5.0% (2/40) respectively, which were not significantly different (χ2=0.372,P>0.05). Obvious abdominal pain, nausea or vomitting occurred in no patients of the two groups. There was no difference in electrolyte level or liver and kidney function between those two groups (P>0.05). 

    Conclusion  Magnesium sulfate combined with compound polyethylene glycol electrolyte is applicable for the bowel preparation before capsule endoscopy.
    【Key words】Capsule endoscopy;Magnesium sulfate;Compound polyethylene glycol electrolyte;Bowel preparation

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个人资料
    张澍田 单位:首都医科大学附属北京友谊医院
    所属科室:消化科
    出生:1964-06-01
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