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新型高清显微内镜在食管早期肿瘤中的诊断价值初探

(2014-10-22 12:29:05)

    新型高清显微内镜在食管早期肿瘤中的诊断价值初探

    王雪珊,徐为然,张帆,王丽波,徐红

    作者单位:130021 吉林,吉林大学白求恩第一医院胃肠内科-内镜中心

    【摘要】 目的  初步探讨高清显微内镜在食管肿瘤诊断中的价值。方法  选择60例患者进行高清显微内镜检查,根据显微内镜图像判定病变性质,以最终病理结果作为金标准,评估高清显微内镜的诊断价值。结果  高清显微内镜对重度异型增生或早癌组织诊断的敏感性、特异性、阳性预测值、阴性预测值和准确率分别为81.22%94.12%81.82%94.12%91.11%,高清显微内镜与病理对重度异型增生或早癌诊断的一致性较高(K=0.760)。结论  高清显微内镜在诊断食管早期肿瘤中具有较高的临床价值。

    【关键词】高清显微内镜,重度异型增生/早癌,卢戈氏液染色,病理

    Diagnostic value of a new high-resolution microendoscopy for early esophageal cancer

    WANG Xue-Shan, XU Wei-Ran, ZHANG Fan, Wang Li-Bo, XU Hong.

    Endoscopy Center of Department of Gastroenterology, the First Bethune  Hospital of Jilin University, Jilin 130021, China.

    Corresponding author: XU Hong, Email: chxuhong@163.com

    [Abstract] Objective To investigate the therapeutic value of high -resolution microendoscopy for early esophageal cancer. Methods A total of 60 patients,who underwent esophageal endoscopy, were included in this study. The therapeutic value of  high-resolution microendoscopy was investigated with reference to pathological results as golden standard. Results: Diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of microendoscopy for high grade dysplasia/early cancer were 81.22%, 94.12%, 81.82%, 94.12%, 91.11%, respectively. Diagnosis of severe dysplasia/carcinoma with high-resolution microendoscopy was highly consistent with that of pathology(K=0.760) .

    Conclusion The high-resolution microendoscopy is of high diagnostic value for early esophagus cancer .

    Keywords: High-resolution microendoscopy, High grade dysplasia/carcinoma, Lugols solution, Pathology

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    徐红 单位:吉林大学第一医院
    所属科室:
    出生:1974-03-17
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